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Browse our expert-rated database of supplement ingredients. Click any row for full details, research references, and products using that form.

GREAT

Energy · Nerve function

Methylcobalamin

Vitamin B12

The active, methylated form of B12 — directly usable by the body without conversion. Highest bioavailability of all B12 forms. Extensive research supporting neurological health and energy metabolism. Unlike Cyanocobalamin, Methylcobalamin requires no hepatic conversion and can cross the blood-brain barrier more effectively.

GREAT

Sleep quality · Muscle relaxation

Magnesium Glycinate

Magnesium

Highly bioavailable chelated form. Gentle on digestion. Supports sleep, stress, and overall relaxation without the laxative effect seen in cheaper magnesium forms.

GREAT

Cell division · Methylation

Methylfolate (5-MTHF)

Vitamin B9

Active, bioavailable form of folate, bypassing the MTHFR conversion step. Essential for cell division, DNA synthesis, and healthy methylation — particularly important for those with MTHFR gene variants.

GREAT

Immune function · Skin health

Zinc Picolinate

Zinc

One of the best-absorbed zinc forms, chelated with picolinic acid. Strong clinical evidence for immune support, skin health, and wound healing.

GOOD

Immune support · Antioxidant

Ascorbic Acid

Vitamin C

Standard, well-researched form of Vitamin C. Good bioavailability. Effective for immune support and as an antioxidant, though less gentle on the stomach than buffered forms.

GOOD

Oxygen transport · Energy

Ferrous Gluconate

Iron

Gentler iron form with good bioavailability and fewer GI side effects than Ferrous Sulfate. A solid middle-ground option for those needing iron supplementation.

GOOD

Brain health · Immune function

Pyridoxine HCl

Vitamin B6

Standard form of B6. Functional and well-researched. P-5-P is more bioavailable but a sound, budget-friendly option for most people.

GOOD

Bone health · Immune support

Cholecalciferol

Vitamin D3

Preferred and most bioavailable form of Vitamin D. Significantly more effective than D2 at raising and maintaining serum levels over time.

GOOD

Digestion · Energy

Magnesium Citrate

Magnesium

Good bioavailability with a gentle laxative effect at higher doses. Well-studied and widely used for general magnesium repletion.

AVERAGE

Bone health · Immune support

Ergocalciferol

Vitamin D2

Plant-derived Vitamin D but significantly less effective than D3 at raising serum levels — generally considered an inferior choice for supplementation.

AVERAGE

Cell division · DNA synthesis

Folic Acid

Vitamin B9

Synthetic folate requiring conversion. Up to 40% of people have MTHFR variants reducing their ability to convert it into the active form efficiently.

AVERAGE

Oxygen transport

Ferrous Sulfate

Iron

Common, inexpensive iron form. Functional but often causes GI side effects including constipation, nausea, and stomach discomfort.

BAD

Energy · Nerve function

Cyanocobalamin

Vitamin B12

Synthetic, non-active B12 form requiring conversion. Contains a cyanide molecule that must be cleared by the body — Methylcobalamin is the superior alternative.

BAD

Digestion

Magnesium Oxide

Magnesium

Very poorly absorbed (~4% absorption rate). Primarily used as a cheap bulking agent rather than for any meaningful magnesium contribution.

BAD

Filler · Colourant

Titanium Dioxide

CI 77891

White colourant with no nutritional value. Banned from EU food use since 2022 due to genotoxicity concerns — a clear red flag in any formula.

BAD

Immune function

Zinc Oxide

Zinc

One of the lowest bioavailability zinc forms. Used due to low cost. Zinc Picolinate is significantly better absorbed and more effective.